| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 4 |
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| Ligand | BDBM459057 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Inhibition Assay |
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| IC50 | 50±n/a nM |
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| Citation |  Bourque, EM; Skerlj, R CXCR4 inhibitors and uses thereof US Patent US10759796 Publication Date 9/1/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| C-X-C chemokine receptor type 4 |
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| Name: | C-X-C chemokine receptor type 4 |
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| Synonyms: | CXC-R4 | CXCR-4 | CXCR4 | CXCR4_BOVIN | Fusin | LCR1 | LESTR | Leukocyte-derived seven transmembrane domain receptor | SDF-1 receptor | Stromal cell-derived factor 1 receptor |
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| Type: | Protein |
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| Mol. Mass.: | 39947.89 |
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| Organism: | Bovine |
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| Description: | P25930 |
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| Residue: | 353 |
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| Sequence: | MEGIRIFTSDNYTEDDLGSGDYDSMKEPCFREENAHFNRIFLPTVYSIIFLTGIVGNGLV
ILVMGYQKKLRSMTDKYRLHLSVADLLFVLTLPFWAVDAVANWYFGKFLCKAVHVIYTVN
LYSSVLILAFISLDRYLAIVHATNSQKPRKLLAEKVVYVGVWLPAVLLTIPDLIFADIKE
VDERYICDRFYPSDLWLVVFQFQHIVVGLLLPGIVILSCYCIIISKLSHSKGYQKRKALK
TTVILILTFFACWLPYYIGISIDSFILLEIIQQGCEFESTVHKWISITEALAFFHCCLNP
ILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
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| BDBM459057 |
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| n/a |
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| Name | BDBM459057 |
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| Synonyms: | US10759796, Compound I-17 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H31BrN6 |
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| Mol. Mass. | 483.447 |
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| SMILES | CN1CCN(CC1)c1cccc2nc([C@H]3CCC[C@H](N3C)c3ncccc3C)c(Br)n12 |r| |
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| Structure | 
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