| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
|---|
| Ligand | BDBM463862 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Radioligand Displacement Assay |
|---|
| Ki | 11.0±n/a nM |
|---|
| Citation |  Kunos, G; Iyer, M; Cinar, R; Rice, KC Cannabinoid receptor mediating iminopyrazole compounds US Patent US10787419 Publication Date 9/29/2020 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 1 |
|---|
| Name: | Cannabinoid receptor 1 |
|---|
| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 52842.52 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | P47746 |
|---|
| Residue: | 473 |
|---|
| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
|
|
|
|---|
| BDBM463862 |
|---|
| n/a |
|---|
| Name | BDBM463862 |
|---|
| Synonyms: | US10787419, Serial # 63 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H20Cl2N6O2S |
|---|
| Mol. Mass. | 551.447 |
|---|
| SMILES | Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)n1cccn1 |t:8| |
|---|
| Structure | 
|
|---|
Search and Browse
