| Reaction Details |
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 | Report a problem with these data |
| Target | Uridine phosphorylase 1 |
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| Ligand | BDBM135803 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Study with Mouse and Human Intestinal Tissue Homogenates |
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| IC50 | <100000±n/a nM |
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| Citation |  Garland, WA; Frenzel, BD; Karg, T Methotrexate adjuvants to reduce toxicity and methods for using the same US Patent US Patent
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| More Info.: | Get all data from this article, Assay Method |
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| Uridine phosphorylase 1 |
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| Name: | Uridine phosphorylase 1 |
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| Synonyms: | UP | UPP1 | UPP1_HUMAN | UPase 1 | UrdPase 1 | Uridine phosphorylase (UPase) |
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| Type: | Enzyme |
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| Mol. Mass.: | 33939.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q16831 |
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| Residue: | 310 |
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| Sequence: | MAATGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGG
SPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLH
ELIKLLYYARCSNVTIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKT
DLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAY
AAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVS
YFIKKKLSKA
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| BDBM135803 |
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| n/a |
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| Name | BDBM135803 |
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| Synonyms: | US8853227, TK- 000006 | USRE48253, Designation TK-000006 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H17N3O5 |
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| Mol. Mass. | 331.3233 |
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| SMILES | OC[C@H]1O[C@@H]2[C@@H](Oc3nc(=O)c(NCc4ccccc4)cn23)[C@@H]1O |r| |
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| Structure | 
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