| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 3 |
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| Ligand | BDBM163635 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HDAC Inhibition |
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| IC50 | 1670±n/a nM |
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| Citation |  Liao, D; Roush, WR; Stowe, RL HDAC inhibitor compounds and methods of treatment US Patent US10807944 Publication Date 10/20/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 3 |
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| Name: | Histone deacetylase 3 |
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| Synonyms: | HD3 | HDAC3 | HDAC3_HUMAN | Histone deacetylase 3 (HDAC3) | Human HDAC3 | RPD3-2 | SMAP45 |
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| Type: | Enzyme |
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| Mol. Mass.: | 48829.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O15379 |
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| Residue: | 428 |
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| Sequence: | MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCR
FHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNN
KICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEA
FYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVI
NQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTV
RNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQ
TIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDN
DKESDVEI
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| BDBM163635 |
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| n/a |
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| Name | BDBM163635 |
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| Synonyms: | SR-3298 | US10807944, Compound RLS2-225 | US11731934, Compound RLS2-225 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H23N3O |
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| Mol. Mass. | 261.3626 |
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| SMILES | CN(C)c1ccc(cc1)C(=O)NNCC1CCCC1 |
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| Structure | 
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