| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
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| Ligand | BDBM50240772 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | MAOA and MAOB In Vitro Activity Experiments |
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| IC50 | 11550±3820 nM |
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| Citation |  Liu, H; Li, J; Wang, J; Su, M; Wang, S; Zhou, Y; Zhu, W; Xu, W; Li, C; Jiang, H; Chen, K Fluorinated cyclopropylamine compound, preparation method therefor, pharmaceutical composition thereof, and uses thereof US Patent US10836743 Publication Date 11/17/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] A |
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| Name: | Amine oxidase [flavin-containing] A |
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| Synonyms: | AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA) |
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| Type: | Protein |
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| Mol. Mass.: | 59689.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21397 |
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| Residue: | 527 |
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| Sequence: | MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
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| BDBM50240772 |
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| n/a |
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| Name | BDBM50240772 |
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| Synonyms: | (1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-phenylcyclopropanamine | (tranylcypromine)2-Phenyl-cyclopropylamine | 2-Phenyl-cyclopropylamine | CHEMBL1179 | Parnate | TRANYLCYPROMINE | TRANYLCYPROMINE HYDROCHLORIDE | US10836743, Compound TCP | US8993808, Tranylcypromine | US9180183, Tranylcypromine | cid_2723716 | rel-Tranylcypromine |
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| Type | Small organic molecule |
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| Emp. Form. | C9H11N |
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| Mol. Mass. | 133.1903 |
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| SMILES | N[C@@H]1C[C@H]1c1ccccc1 |r| |
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| Structure | 
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