| Reaction Details |
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 | Report a problem with these data |
| Target | Polyphenol oxidase 1 |
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| Ligand | BDBM473775 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Tyrosinase Inhibition Assay |
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| IC50 | 11000±n/a nM |
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| Citation |  Jia, Q; Zhao, J Diarylalkanes as potent inhibitors of binuclear enzymes US Patent US10857082 Publication Date 12/8/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Polyphenol oxidase 1 |
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| Name: | Polyphenol oxidase 1 |
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| Synonyms: | PPO1 | PPO1_AGABI | Polyphenol oxidase | Tyrosinase |
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| Type: | Enzyme |
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| Mol. Mass.: | 63902.83 |
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| Organism: | Agaricus bisporus (White button mushroom) |
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| Description: | Q00024 |
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| Residue: | 568 |
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| Sequence: | MSHLLVSPLGGGVQPRLEINNFVKNDRQFSLYVQALDRMYATPQNETASYFQVAGVHGYP
LIPFDDAVGPTEFSPFDQWTGYCTHGSTLFPTWHRPYVLILEQILSGHAQQIADTYTVNK
SEWKKAATEFRHPYWDWASNSVPPPEVISLPKVTITTPNGQKTSVANPLMRYTFNSVNDG
GFYGPYNQWDTTLRQPDSTGVNAKDNVNRLKSVLKNAQASLTRATYDMFNRVTTWPHFSS
HTPASGGSTSNSIEAIHDNIHVLVGGNGHMSDPSVAPFDPIFFLHHANVDRLIALWSAIR
YDVWTSPGDAQFGTYTLRYKQSVDESTDLAPWWKTQNEYWKSNELRSTESLGYTYPEFVG
LDMYNKDAVNKTISRKVAQLYGPQRGGQRSLVEDLSNSHARRSQRPAKRSRLGQLLKGLF
SDWSAQIKFNRHEVGQSFSVCLFLGNVPEDPREWLVSPNLVGARHAFVRSVKTDHVAEEI
GFIPINQWIAEHTGLPSFAVDLVKPLLAQGLQWRVLLADGTPAELDSLEVTILEVPSELT
DDEPNPRSRPPRYHKDITHGKRGGCREA
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| BDBM473775 |
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| n/a |
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| Name | BDBM473775 |
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| Synonyms: | 1-(2-hydroxy-4-methoxyphenyl)-3-(3',4',5'-trimethoxyphenyl)-1-propanol | US10857082, Table 2.9 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24O6 |
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| Mol. Mass. | 348.3903 |
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| SMILES | COc1ccc(C(O)CCc2cc(OC)c(OC)c(OC)c2)c(O)c1 |
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| Structure | 
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