| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM474273 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FLIPR and cAMP Inhibition Assay |
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| IC50 | 5.90±n/a nM |
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| Citation |  Zeng, Q; Qi, C; Tsui, H; Yang, Z; Zhang, X Triazolo-pyrimidine compounds and uses thereof US Patent US10858365 Publication Date 12/8/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | AA2AR_MOUSE | Adenosine A2a receptor | Adenosine receptor A2a | Adora2a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44984.04 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_479903 |
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| Residue: | 410 |
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| Sequence: | MGSSVYIMVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFA
ITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGMRAKG
IIAICWVLSFAIGLTPMLGWNNCSQKDENSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAF
VLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALC
WLPLHIINCFTFFCSTCQHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRT
HVLRRQEPFRAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSAPHSGRRPNGYTLGP
GGGGSTQGSPGDVELLTQEHQEGQEHPGLGDHLAQGRVGTASWSSEFAPS
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| BDBM474273 |
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| n/a |
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| Name | BDBM474273 |
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| Synonyms: | 5-(5-amino-2-(2,6-difluorobenzyl)-7-(thiazol-2- yl)-[1,2,4]triazolo[1,5-c]pyrimidin-8-yl)-l-methyl pyridin-2(lH)-one | US10858365, Compound 44 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H15F2N7OS |
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| Mol. Mass. | 451.452 |
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| SMILES | Cn1cc(ccc1=O)-c1c(nc(N)n2nc(Cc3c(F)cccc3F)nc12)-c1nccs1 |
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| Structure | 
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