| Reaction Details |
|---|
 | Report a problem with these data |
| Target | ADP-ribosylation factor 6 |
|---|
| Ligand | BDBM474956 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Biochemical Assay |
|---|
| IC50 | 0.660±n/a nM |
|---|
| Citation |  Ostanin, K; Shenderovich, M; Bajji, A; Cioffi, CL; Moss, N; Vankayalapati, H; Li, D Arf6 inhibitors and methods of synthesis and use thereof US Patent US10849901 Publication Date 12/1/2020 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| ADP-ribosylation factor 6 |
|---|
| Name: | ADP-ribosylation factor 6 |
|---|
| Synonyms: | ARF6 | ARF6_HUMAN |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 20087.47 |
|---|
| Organism: | Human |
|---|
| Description: | P62330 |
|---|
| Residue: | 175 |
|---|
| Sequence: | MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFN
VWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIF
ANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS
|
|
|
|---|
| BDBM474956 |
|---|
| n/a |
|---|
| Name | BDBM474956 |
|---|
| Synonyms: | US10849901, Compound 6 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H14Cl2F3N3O2 |
|---|
| Mol. Mass. | 516.299 |
|---|
| SMILES | FC(F)(F)c1nn2c([nH]c(cc2=O)-c2ccc(Oc3ccccc3)cc2)c1-c1ccc(Cl)c(Cl)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
