| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Small conductance calcium-activated potassium channel protein 2 |
|---|
| Ligand | BDBM168436 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Voltage-Clamp Assay |
|---|
| pH | 7.35±n/a |
|---|
| Temperature | 298.15±n/a K |
|---|
| EC50 | 1.4e+4± 5e+3 nM |
|---|
| Comments | extracted |
|---|
| Citation |  PubChem, PC; Wulff, H; Coleman, N; Jenkins, DP Methods for treating seizure disorders and pain US Patent US9675591 Publication Date 6/13/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Small conductance calcium-activated potassium channel protein 2 |
|---|
| Name: | Small conductance calcium-activated potassium channel protein 2 |
|---|
| Synonyms: | KCNN2_RAT | Kcnn2 | Small conductance calcium-activated potassium channel | Small conductance calcium-activated potassium channel protein 2 | Small conductance calcium-activated potassium channel protein 2 (KCa2.2) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 63876.72 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P70604 |
|---|
| Residue: | 580 |
|---|
| Sequence: | MSSCRYNGGVMRPLSNLSSSRRNLHEMDSEAQPLQPPASVVGGGGGASSPSAAAAASSSA
PEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGGGGGSGHGSSSGTKSSKKKNQNIGY
KLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTI
ILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTA
RLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTR
FVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSI
GYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRV
KNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTL
VDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDF
IETQMENYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS
|
|
|
|---|
| BDBM168436 |
|---|
| n/a |
|---|
| Name | BDBM168436 |
|---|
| Synonyms: | US9675591, SKA-19 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C8H5F3N2S2 |
|---|
| Mol. Mass. | 250.264 |
|---|
| SMILES | Nc1nc2ccc(SC(F)(F)F)cc2s1 |
|---|
| Structure | 
|
|---|
Search and Browse
