| Reaction Details |
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 | Report a problem with these data |
| Target | Small conductance calcium-activated potassium channel protein 3 |
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| Ligand | BDBM168436 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Voltage-Clamp Assay |
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| pH | 7.35±n/a |
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| Temperature | 298.15±n/a K |
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| EC50 | 1.5e+4± 5e+3 nM |
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| Comments | extracted |
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| Citation |  PubChem, PC; Wulff, H; Coleman, N; Jenkins, DP Methods for treating seizure disorders and pain US Patent US9675591 Publication Date 6/13/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Small conductance calcium-activated potassium channel protein 3 |
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| Name: | Small conductance calcium-activated potassium channel protein 3 |
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| Synonyms: | K3 | KCNN3 | KCNN3_HUMAN | Small conductance calcium-activated potassium channel protein 3 | Small conductance calcium-activated potassium channel protein 3 (KCa2.3) |
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| Type: | Protein |
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| Mol. Mass.: | 82053.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9UGI6 |
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| Residue: | 731 |
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| Sequence: | MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQ
PQPPQLQQQQQQQQQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAIL
HPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKY
SGGVMKPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNAT
HNHQHAGTTASSTTFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVI
ETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTY
ERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIAR
VMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRV
CERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVA
VVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKH
QRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLE
SKLEHLTASFNSLPLLIADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSSTS
FPTPYTSSSSC
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| BDBM168436 |
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| n/a |
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| Name | BDBM168436 |
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| Synonyms: | US9675591, SKA-19 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H5F3N2S2 |
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| Mol. Mass. | 250.264 |
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| SMILES | Nc1nc2ccc(SC(F)(F)F)cc2s1 |
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| Structure | 
|
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