| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-synuclein |
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| Ligand | BDBM50185987 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Direct Determination By Fluorescence |
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| Kd | 16.1±6 nM |
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| Citation |  Routier, S; Suzenet, F; Chalon, S; Buron, F; Vercouillie, J; Melki, R; Boiaryna, L; Guilloteau, D; Pieri, L Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases US Patent US10906900 Publication Date 2/2/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Alpha-synuclein |
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| Name: | Alpha-synuclein |
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| Synonyms: | NACP | PARK1 | SNCA | SYUA_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 14451.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37840 |
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| Residue: | 140 |
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| Sequence: | MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
|
|
|
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| BDBM50185987 |
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| n/a |
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| Name | BDBM50185987 |
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| Synonyms: | 2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2-yl)ethylidene)malononitrile | CHEMBL207649 | US10906900, FDDNP | US9452985, FDDNP (reference for comparison) |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16FN3 |
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| Mol. Mass. | 293.3381 |
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| SMILES | [#6]-[#7](-[#6]-[#6]F)-c1ccc2cc(ccc2c1)-[#6](\[#6])=[#6](\C#N)C#N |
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| Structure | 
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