Reaction Details |
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Target | Alpha-synuclein |
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Ligand | BDBM50492518 |
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Substrate/Competitor | n/a |
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Meas. Tech. | In Vitro Direct Determination By Fluorescence |
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Kd | 24.3±20 nM |
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Citation | Routier, S; Suzenet, F; Chalon, S; Buron, F; Vercouillie, J; Melki, R; Boiaryna, L; Guilloteau, D; Pieri, L Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases US Patent US10906900 Publication Date 2/2/2021 |
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More Info.: | Get all data from this article, Assay Method |
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Alpha-synuclein |
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Name: | Alpha-synuclein |
Synonyms: | NACP | PARK1 | SNCA | SYUA_HUMAN |
Type: | Protein |
Mol. Mass.: | 14451.42 |
Organism: | Homo sapiens (Human) |
Description: | P37840 |
Residue: | 140 |
Sequence: | MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
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BDBM50492518 |
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n/a |
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Name | BDBM50492518 |
Synonyms: | Florbetapir | US10906900, AV45 |
Type | Small organic molecule |
Emp. Form. | C20H25FN2O3 |
Mol. Mass. | 360.4225 |
SMILES | CNc1ccc(\C=C\c2ccc(OCCOCCOCCF)nc2)cc1 |
Structure |
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