| Reaction Details |
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 | Report a problem with these data |
| Target | Programmed cell death protein 1 |
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| Ligand | BDBM482526 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme-Linked Immunosorbent Assay ELISA |
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| IC50 | <5±n/a nM |
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| Citation |  Lange, C; Malathong, V; Mali, VR; McMahon, J; McMurtrie, DJ; Punna, S; Roth, HS; Singh, R; Wang, Y; Yang, J; Zhang, P Immunomodulator compounds US Patent US10919852 Publication Date 2/16/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Programmed cell death protein 1 |
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| Name: | Programmed cell death protein 1 |
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| Synonyms: | CD_antigen=CD279 | PD1 | PDCD1 | PDCD1_HUMAN | Programmed cell death protein 1 | Protein PD-1 | hPD-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 31650.07 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_108437 |
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| Residue: | 288 |
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| Sequence: | MQIPQAPWPVVWAVLQLGWRPGWFLDSPDRPWNPPTFSPALLVVTEGDNATFTCSFSNTS
ESFVLNWYRMSPSNQTDKLAAFPEDRSQPGQDCRFRVTQLPNGRDFHMSVVRARRNDSGT
YLCGAISLAPKAQIKESLRAELRVTERRAEVPTAHPSPSPRPAGQFQTLVVGVVGGLLGS
LVLLVWVLAVICSRAARGTIGARRTGQPLKEDPSAVPVFSVDYGELDFQWREKTPEPPVP
CVPEQTEYATIVFPSGMGTSSPARRGSADGPRSAQPLRPEDGHCSWPL
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| BDBM482526 |
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| n/a |
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| Name | BDBM482526 |
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| Synonyms: | US10919852, Compound TABLE 1.225 | US11708326, Compound TABLE 1.225 |
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| Type | Small organic molecule |
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| Emp. Form. | C45H48ClFN4O4 |
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| Mol. Mass. | 763.338 |
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| SMILES | Cc1c(OCCCN2CCC(F)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CN[C@H]2CCC[C@H]2O)cc1Cl |r| |
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| Structure | 
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