| Reaction Details |
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 | Report a problem with these data |
| Target | AP-4 complex subunit sigma-1 |
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| Ligand | BDBM484117 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Human Sigma-1 Receptor Radioligand Assay |
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| Ki | <100±n/a nM |
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| Citation |  Virgili-Bernado, M; Almansa-Rosales, C; Alegret-Molina, C Oxadiazaspiro compounds for the treatment of drug abuse and addiction US Patent US10927128 Publication Date 2/23/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| AP-4 complex subunit sigma-1 |
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| Name: | AP-4 complex subunit sigma-1 |
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| Synonyms: | AP-4 complex subunit sigma-1 | AP4S1 | AP4S1_HUMAN | Sigma-1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 17000.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Sigma-1 0 HUMAN::Q9Y587 |
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| Residue: | 144 |
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| Sequence: | MIKFFLMVNKQGQTRLSKYYEHVDINKRTLLETEVIKSCLSRSNEQCSFIEYKDFKLIYR
QYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDIMFNLDKVHIILDEMVLN
GCIVETNRARILAPLLILDKMSES
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| BDBM484117 |
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| n/a |
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| Name | BDBM484117 |
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| Synonyms: | (S)-9-(2-(3-fluoropyridin-2-yl)ethyl-4-isopropyl- 2-methyl-1-oxa-4,9-diazaspiro[5.5]undecane | US10927128, Example 38 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H30FN3O |
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| Mol. Mass. | 335.4594 |
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| SMILES | CC(C)N1C[C@H](C)OC2(CCN(CCc3ncccc3F)CC2)C1 |r| |
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| Structure | 
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