| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glycogen synthase kinase-3 beta |
|---|
| Ligand | BDBM484660 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Kinase Assay |
|---|
| EC50 | 1.000±n/a nM |
|---|
| Citation |  Kc, SK; Mak, CC; Mittapalli, GK; Hofilena, BJ; Eastman, BW; Cao, J; Chiruta, C; Bollu, V 5-heteroaryl substituted indazole-3-carboxamides and preparation and use thereof US Patent US10934297 Publication Date 3/2/2021 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glycogen synthase kinase-3 beta |
|---|
| Name: | Glycogen synthase kinase-3 beta |
|---|
| Synonyms: | GSK-3 beta | GSK-3, beta | GSK3B | GSK3B_HUMAN | Glycogen synthase kinase 3 beta (GSK3B) | Glycogen synthase kinase 3-beta (GSK3B) | Glycogen synthase kinase-3 beta (GSK-3B) | Glycogen synthase kinase-3 beta (GSK3 Beta) | Glycogen synthase kinase-3 beta (GSK3B) | Glycogen synthase kinase-3B (GSK-3B) | Glycogen synthase kinase-3beta (GSK3B) | Serine/threonine-protein kinase GSK3B |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 46756.38 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P49841 |
|---|
| Residue: | 420 |
|---|
| Sequence: | MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALF
NFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANTGDRGQTNNAASASASNST
|
|
|
|---|
| BDBM484660 |
|---|
| n/a |
|---|
| Name | BDBM484660 |
|---|
| Synonyms: | US10934297, Compound 53 | US11713320, Compound 53 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H16FN7O |
|---|
| Mol. Mass. | 377.375 |
|---|
| SMILES | Fc1ccc(NC(=O)c2n[nH]c3ccc(cc23)-c2nnc3CNCCn23)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
