| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytosolic phospholipase A2 |
|---|
| Ligand | BDBM301777 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In Vitro cPLA2 Assay |
|---|
| IC50 | >5000±n/a nM |
|---|
| Citation |  Kokotos, G; Johansen, B; Magrioti, V; Tsakos, M 2-oxothiazole compounds and method of using same for chronic inflammatory disorders US Patent US9597318 Publication Date 3/21/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytosolic phospholipase A2 |
|---|
| Name: | Cytosolic phospholipase A2 |
|---|
| Synonyms: | CPLA2 | Lysophospholipase | PA24A_HUMAN | PLA2G4 | PLA2G4A | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2 | Phospholipase A2 group IVA |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 85219.30 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P47712 |
|---|
| Residue: | 749 |
|---|
| Sequence: | MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRT
RHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTVSSMKVGEKKEV
PFIFNQVTEMVLEMSLEVCSCPDLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEG
LHSARDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSH
PDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIG
ETLIHNRMNTTLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYG
TFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEE
LENITTKHIVSNDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFN
TREGRAGKVHNFMLGLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFERIYEPLDV
KSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMN
KLPFPKIDPYVFDREGLKECYVFKPKNPDMEKDCPTIIHFVLANINFRKYRAPGVPRETE
EEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKEAMVESIEYRR
QNPSRCSVSLSNVEARRFFNKEFLSKPKA
|
|
|
|---|
| BDBM301777 |
|---|
| n/a |
|---|
| Name | BDBM301777 |
|---|
| Synonyms: | US9597318, Code GK159 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H17NOS |
|---|
| Mol. Mass. | 295.399 |
|---|
| SMILES | O=C(CCCCc1ccccc1)c1nc2ccccc2s1 |
|---|
| Structure | 
|
|---|
Search and Browse
