| Reaction Details |
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 | Report a problem with these data |
| Target | Proteinase-activated receptor 2 |
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| Ligand | BDBM429569 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | IP-One HTRF Assay |
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| IC50 | 860±n/a nM |
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| Citation |  Cumming, JG; Wu, FX; Edman, KH; Chen, H; Brown, DG; Burli, RW; Johnstone, SD; Brown, GA; Tehan, BG; Teobald, BJ; Congreve, MS Inhibitors of protease-activated receptor-2 US Patent US10995072 Publication Date 5/4/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteinase-activated receptor 2 |
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| Name: | Proteinase-activated receptor 2 |
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| Synonyms: | F2RL1 | GPR11 | PAR2 | PAR2_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44152.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1497756 |
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| Residue: | 397 |
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| Sequence: | MRSPSAAWLLGAAILLAASLSCSGTIQGTNRSSKGRSLIGKVDGTSHVTGKGVTVETVFS
VDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALA
DLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNP
MGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMF
NYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICF
TPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALL
CRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY
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| BDBM429569 |
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| n/a |
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| Name | BDBM429569 |
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| Synonyms: | US10550089, Example 43 | US10550089, Example 44 | US10550089, Example 45 | US10995072, Example 43 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H13FN2O2 |
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| Mol. Mass. | 272.2743 |
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| SMILES | OC(c1ncc[nH]1)c1ccc(F)c2occ(C3CC3)c12 |
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| Structure | 
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