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Assay Method Information |
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| | In Vitro Assays |
| Description: | A compound described herein can be tested in vitro for inhibition of wild-type RET and various mutant RET kinases, including e.g., RET V804L, RET V804M, and RET M918T kinases, as well as CCDC6-RET and KIF5B-RET fusion kinases. The IC50 can be calculated. |
| Affinity data for this assay | |
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