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| | Cotransfection Assay |
| Description: | Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values are the molar concentration of the test compound that affords 50% of the maximal reporter activity, or the molar concentrations required to decrease the activity of 100 uM CDCA by 50%. |
| Affinity data for this assay | |
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