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Assay Method Information

Assay Name:  ChEMBL_1581635 (CHEMBL3817398)
Description:  Inhibition of C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as 7-benzyloxy-4-(trifluoromethyl)coumarin O-debenzylation pretreated 2 mins followed by NADPH addition by fluorometric method in presence of rat cytochrome P450 reductase
Affinity data for this assay
 

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Last update November 1, 2007
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