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Assay Method Information

Assay Name:  Enzyme Binding Assays (Kinomescan)
Description:  Kinase enzyme binding activities of the compound disclosed herein may be determined using a proprietary assay which measures active site-directed competition binding to an immobilized ligand (Fabian, M. A. et al., Nature Biotechnol., 2005, 23:329-336). These assays may be conducted by DiscoverX (formerly Ambit; San Diego, Calif.). The percentage inhibition produced by incubation with a test compound may be calculated relative to the non-inhibited control.
Affinity data for this assay
 

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Last update November 1, 2007
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