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Assay Method Information |
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| | Fluorescence Polarization Assay (1% in DMSO) |
| Description: | Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as described in Buckley et al. JACS, 2012, 134, 4465-4468, WO 2013/106643, and US 2014-0356322, which are incorporated herein by reference in their entirety for all purposes. |
| Affinity data for this assay | |
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