Assay Method Information |
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| ChEMBL_1760791 (CHEMBL4195799) |
Description: | Antagonist activity at prolink-tagged TrkA in human U2OS cells assessed as inhibition of beta-NGF-induced receptor phosphorylation by measuring reduction in EA-tagged SH2 protein recruitment preincubated for 30 mins followed by beta-NGF stimulation measured after 2 hrs by PathHunter enzyme complementation assay |
Affinity data for this assay | |
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