Assay Method Information |
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| ChEMBL_2241391 (CHEMBL5155601) |
Description: | Inhibition of CYP3A4 in human liver microsomes assessed as reduction in 1'-hydroxy midazolam formation using midazolam as substrate preincubated for 20 mins in presence of NADPH followed by incubation with substrate for 10 mins by LC-MS/MS analysis |
Affinity data for this assay | |
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