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Assay Method Information |
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| | ChEMBL_1838748 (CHEMBL4338881) |
| Description: | Inhibition of full length C-terminal His8 tagged IDH1 R132H mutant (1 to 414 residues) (unknown origin) homodimer expressed in Escherichia coli BE3 cells assessed as reduction in NADPH consumption using alpha-ketoglutarate as substrate after 60 mins by Diaphorase/Resazurin dye based fluorescence assay |
| Affinity data for this assay | |
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