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Assay Method Information |
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| | ChEMBL_1612841 (CHEMBL3854641) |
| Description: | Inhibition of human DNA polymerase kappa (19 to 526 residues)-mediated TLS past acrolein derived ring-opened reduced form of gamma-HOPdG lesions preincubated for 15 mins followed by DNA substrate addition measured after 30 mins in presence of dCTP and dGTP by radioactive gel-based primer extension assay |
| Affinity data for this assay | |
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