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Assay Method Information |
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| | ChEMBL_1629240 (CHEMBL3871866) |
| Description: | Inhibition of CYP2D6 in human liver microsomes assessed as reduction in formation of 1'-hydroxy-bufuralol from bufuralol preincubated with enzyme followed by substrate and beta-NADPH addition measured after 10 mins by LC-MS/MS analysis |
| Affinity data for this assay | |
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