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Assay Method Information |
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| | ChEMBL_2300367 |
| Description: | Inhibition of human N-terminal 6His-tagged IDH1 R132H mutant expressed in Escherichia coli Rosetta2 (DE3) assessed as effect on intracellular 2-HG level incubated for 60 mins in presence of alpha-ketoglutarate and NADPH by LC/MS/MS analysis |
| Affinity data for this assay | |
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