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Assay Method Information |
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| | ChEMBL_1580958 (CHEMBL3812626) |
| Description: | Antagonist activity against ATP-gated P2X7 receptor in LPS-stimulated human whole blood assessed as reduction in P2X7 agonist 2'(3')-O-(4-benzoylbenzoyl) adenosine 5'-triphosphate-induced IL-1beta incubated for 30 mins after 1 hr pre-treatment with LPS followed by Bz-ATP-stimulation for 1.5 hrs by ELISA |
| Affinity data for this assay | |
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