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Assay Method Information |
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| | ChEMBL_2262827 (CHEMBL5217838) |
| Description: | Inhibition of NLRP3 inflammasome activation in LPS/nigericin stimulated human THP1-ASC-GFP cells assessed as decrease in ASC speck formation preincubated with LPS for 3 hrs followed by compound addition for 30 mins and further stimulated with nigericin by microscopic analysis |
| Affinity data for this assay | |
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