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Assay Method Information |
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| | ChEMBL_1824964 (CHEMBL4324728) |
| Description: | Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as pEC50 for CCL3-stimulated [35S]GTPgammaS binding at 100 nM preincubated for 30 mins followed by [35S]GTPgammaS addition and measured after 90 mins (Rvb = 8.42 +/- 0.06 No_unit) |
| Affinity data for this assay | |
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