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Assay Method Information |
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| | ChEMBL_1991445 (CHEMBL4625180) |
| Description: | Binding affinity to murine DNMT3A catalytic domain assessed as enzyme-DNA complex formation at 30 uM using 30-mer duplex DNA (22 AT bp) as substrate preincubated for 30 mins followed by enzyme addition by fluorescence polarization assay (Rvb = 0.4 +/- 0.1 uM) |
| Affinity data for this assay | |
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