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Compounds Sorted by Binding Data per Compound

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29
30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55
56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81
82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105
106 107 109 110 111 112 113 114 118 119 120 121 122 123 124 125 126 127 128
130 131 134 136 137 138 139 140 141 146 147 148 150 152 153 154 156 157 158
159 160 161 162 163 164 165 166 168 169 171 172 173 179 185 186 188 190 194
195 199 205 207 208 212 219 221 222 223 224 225 226 233 241 243 255 261 277
285 291 293 303 305 307 324 326 330 333 335 336 337 341 357 360 366 386 389
411 442 443 444 445 446 447 448 450 453 454 456 458 459 460 461 463 465 467
469 482 496 505 511 515 516 526 529 539 555 581 773 790 804 821 824 831 837
839 847 849 853 855 868 871 880 913 922 923 931 938 960 965 989 995 997 1013
1027 1054 1096 1125 1196 1353 1429 1598
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Enz. Inhib. Data
ITC Data
Binding Targets
Alternate Compound Names
107 Ki 2 IC50 2 Kd
  • β-Carbonic anhydrase 2 (CA 2)
  • Alpha carbonic anhydrase
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonate dehydratase
  • Carbonic Anhydrase (hpCA)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase (mtCA 3)
  • Carbonic Anhydrase 2 (Can2)
  • Carbonic Anhydrase III
  • Carbonic Anhydrase IV
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Carbonic anhydrase, alpha family
  • Carbonic anhydrases; II & IX
  • Delta carbonic anhydrase
  • beta-Carbonic Anhydrase
  • 4-(2-hydroxyethyl)benzene-1-sulfonamide
  • CHEMBL6784
  • JMC522226 Compound 21
  • JMC523116 Compound 21
  • aromatic/heteroaromatic sulfonamide 22
23 Ki 75 IC50 2 Kd 10 EC50
0 ΔG°
  • 1-deoxy-D-xylulose 5-phosphate reductoisomerase
  • 3-oxoacyl-acyl-carrier protein reductase
  • ATP-binding cassette sub-family G member 2
  • Acetylcholinesterase
  • Adenosine receptor A1
  • Aldose reductase
  • Aldose reductase (ALR2)
  • Aldose reductase (AR)
  • Amine oxidase [flavin-containing] A
  • Amine oxidase [flavin-containing] B
  • Angiotensin-converting enzyme
  • Arachidonate 15-lipoxygenase
  • Arachidonate 5-lipoxygenase
  • Aurora kinase B
  • Beta amyloid A4 protein
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 3 (CA III)
  • Carbonic anhydrase 4
  • Carbonic anhydrase 7
  • Cell division protein kinase 5
  • Cholinesterase
  • Collagenase
  • Cruzipain
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 6 (CDK6)
  • Cyclin-dependent kinase 2
  • Cyclooxygenase
  • Cytochrome P450 1A
  • Cytochrome P450 1A1
  • Cytochrome P450 1B1
  • DNA topoisomerase 1
  • Death-associated protein kinase 1
  • Dipeptidyl peptidase III
  • Dopamine Transporter (DAT)
  • Enoyl-ACP Reductase (FabI)
  • Enoyl-acyl-carrier protein reductase
  • Fatty acid synthase
  • G-protein coupled receptor 35
  • Glycogen Synthase Kinase-3, beta
  • Glycogen synthase kinase-3 beta
  • Glyoxalase 1 (GLO1)
  • Human diphtheria toxin-like ADP-ribosyltransferase (ARTD5 or PARP5a)
  • Human diphtheria toxin-like ADP-ribosyltransferase (ARTD6 or PARP5b)
  • Human immunodeficiency virus type 1 integrase
  • Leucine aminopeptidase (LAP)
  • Lipoxygenase-1
  • Lymphocyte differentiation antigen CD38
  • Matrix metalloproteinase-1 (cd-MMP-1)
  • Matrix metalloproteinase-12 (MMP12)
  • Mitogen-activated protein kinase 10
  • Mitogen-activated protein kinase 14
  • NADPH oxidase 4
  • P-glycoprotein 1
  • POsterior Segregation family member (pos-1)
  • Peroxisome proliferator-activated receptor gamma
  • Poly [ADP-ribose] polymerase 1
  • Protein polybromo-1
  • RecName: Full=Zinc finger protein mex-5
  • Serine/threonine-protein kinase PIM
  • Sialidase
  • Sialidase 2
  • Stromelysin-1
  • Transcriptional Regulator TtgR
  • Transthyretin
  • Trypsin
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Xanthine dehydrogenase
  • Xanthine dehydrogenase/oxidase
  • Zinc aminopeptidase
  • alpha-Amylase
  • large T antigen
  • lens epithelium-derived growth factor p75
  • 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
  • 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-chromen-4-one
  • CHEMBL151
  • Luteolin (27)
  • Luteolin (4)
  • cid_5280445
  • luteolin
95 Ki 15 IC50 1 EC50
  • 5-HT1
  • 5-HT3A Serotonin Receptor
  • 5-Hydroxytryptamine receptor 6 (5-HT6)
  • 5-Hydroxytryptamine receptor 7 (5-HT7)
  • 5-hydroxytryptamine receptor 1A (5-HT1A)
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • ADRA2C
  • Adenylate cyclase
  • Adrenergic Alpha
  • Adrenergic receptor alpha-2
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Androgen receptor
  • Bfl-1
  • Bile salt export pump
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • DOPAMINE
  • DRD1
  • DRD2
  • Dopamine D1 receptor
  • Dopamine D2 receptor
  • Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor
  • Dopamine D5 receptor
  • Dopamine receptor
  • Dopamine receptors; D2 & D4
  • HTR6
  • Histamine H1 receptor
  • Histamine receptor (H3)
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • NADPH oxidase 1
  • P-glycoprotein 1
  • Pleiotropic ABC efflux transporter of multiple drugs
  • Serotonin (5-HT) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma non-opioid intracellular receptor 1
  • Sodium channel protein type I I alpha subunit
  • TPA: Essential protein of the mitochondrial intermembrane space
  • Trypanothione reductase
  • Twik-RElated Potassium (K+) channel 1 (TREK1)
  • ubiquitin-conjugating enzyme E2 N
  • 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride
  • 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride
  • 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride
  • FLUPHENAZINE
  • FLUPHENAZINE HYDROCHLORIDE
  • MLS001076508
  • SMR000058411
  • cid_3372
  • cid_6602611
35 Ki 48 IC50 4 Kd 24 EC50
  • ATP-binding cassette sub-family G member 2
  • Acyl Cholesterol Acyltransferase 1 (ACAT-1)
  • Adrenergic Alpha
  • Androgen Receptor
  • Androgen receptor
  • Anti-estrogen binding site (AEBS)
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • C-8 sterol isomerase
  • Cytochrome P450 2C9
  • Estrogen receptor
  • G-protein coupled bile acid receptor 1
  • Glucocorticoid receptor
  • Intestinal fatty acid-binding protein (hIFABP)
  • Liver fatty acid binding protein (rat L-FABP)
  • Mineralocorticoid receptor
  • Organic anion-transporting polypeptide 1D1 (Oatp1d1)
  • P-glycoprotein 1
  • Progesterone receptor
  • Sigma non-opioid intracellular receptor 1
  • Solute carrier family 22 member 2
  • Solute carrier family 22 member 3
  • Steroid 5-alpha-reductase
  • Sterol 14α-demethylase (CYP51)
  • Testis-specific androgen-binding protein
  • (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
  • CHEMBL103
  • progesterone