34 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Discovery of triazole aminopyrazines as a highly potent and selective series of PI3Kd inhibitors.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Astrazeneca
Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-ß hydrolysis.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
University of Lille
Synthesis and enzymatic evaluation of novel partially fluorinated thiol dual ACE/NEP inhibitors.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Dipartimento Di Chimica
Endothelin-converting enzyme-1 inhibition and growth of human glioblastoma cells.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
University Institute of Pathology
Potent and selective non-peptidic inhibitors of endothelin-converting enzyme-1 with sustained duration of action.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Novartis Institute For Biomedical Research
Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
F. Hoffmann-La Roche
Design and synthesis of potent, selective inhibitors of endothelin-converting enzyme.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Novartis Pharmaceuticals
Hydroxamic acids as potent inhibitors of endothelin-converting enzyme from human bronchiolar smooth muscle.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Berlex Laboratories
Phosphorus-containing inhibitors of endothelin converting enzyme: effects of the electronic nature of phosphorus on inhibitor potency.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Monsanto
Potent non-peptidic dual inhibitors of endothelin-converting enzyme and neutral endopeptidase 24.11![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
Design and synthesis of phosphinic acids that triply inhibit endothelin converting enzyme, angiotensin converting enzyme and neutral endopeptidase 24.11![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
Phosphinic tripeptides as dual angiotensin-converting enzyme C-domain and endothelin-converting enzyme-1 inhibitors.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cea
Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder. Synthesis and activity of functionalized glutaramides.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Pfizer
Novel, selective indole-based ECE inhibitors: lead optimization via solid-phase and classical synthesis.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Bayer Healthcare
Synthesis and biological activity of potent heterocyclic thiol-based inhibitors of endothelin-converting enzyme-1.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Novartis Institute For Biomedical Research
N-[2-(Indan-1-yl)-3-mercapto-propionyl] amino acids as highly potent inhibitors of the three vasopeptidases (NEP, ACE, ECE): In vitro and In vivo activities.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
University of Paris
Synthesis of triazole-Tethered pyrrolidine libraries: novel ECE inhibitors.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
F. Hoffmann-La Roche
2-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)- and 2-(2,2-dioxo-1,4-dihydro-2H-2lambda6-benzo[1,2,6]thiadiazin-3-yl)-N-hydroxy-acetamides as potent and selective peptide deformylase inhibitors.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
F. Hoffmann-La Roche
Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-?-lactamases.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Qpex Biopharma
Synthesis and biological activity of novel potent endothelin-converting enzyme-1 inhibitors.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Novartis Institute For Biomedical Research
Discovery of Fluoromethylketone-Based Peptidomimetics as Covalent ATG4B (Autophagin-1) Inhibitors.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Roche Pharma Research and Early Development
Design and synthesis of potent thiol-based inhibitors of endothelin converting enzyme-1.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Novartis Institute For Biomedical Research
Synthesis of a phostone glycomimetic of the endothelin converting enzyme inhibitor phosphoramidon.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Université
Synthesis of novel substituted pyridines as inhibitors of endothelin converting enzyme-1 (ECE-1).![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Warner-Lambert
Highly selective and orally active inhibitors of type IV collagenase (MMP-9 and MMP-2): N-sulfonylamino acid derivatives.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Shionogi