BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.7M data for 1.2M Compounds and 9.0K Targets. Of those, 1,244K data for 572K Compounds and 4.4K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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8 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Structure-activity relationship in a purine-scaffold compound series with selectivity for the endoplasmic reticulum Hsp90 paralog Grp94.EBI
Sloan-Kettering Institute For Cancer Research
Experimental and structural testing module to analyze paralogue-specificity and affinity in the Hsp90 inhibitors series.EBI
Memorial Sloan-Kettering Cancer Center
Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90.EBI
Infinity Pharmaceuticals
Discovery of a Potent Grp94 Selective Inhibitor with Anti-Inflammatory Efficacy in a Mouse Model of Ulcerative Colitis.EBI
China Pharmaceutical University
Resorcinol-Based Grp94-Selective Inhibitors.EBI
The University of Kansas
Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding.EBI
Hauptman-Woodward Medical Research Institute