PMID

Data

Article Title

Organization

Scaffold Repurposing of Nucleosides (Adenosine Receptor Agonists): Enhanced Activity at the Human Dopamine and Norepinephrine Sodium Symporters.

National Institute of Diabetes and Digestive and Kidney Diseases

Design, synthesis and SAR studies of GABA uptake inhibitors derived from 2-substituted pyrrolidine-2-yl-acetic acids.

Ludwig-Maximilians-Universit£T M£Nchen

Ether modifications to 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine (SA4503): effects on binding affinity and selectivity for sigma receptors and monoamine transporters.

University of Missouri

6-(3,4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane: a new potent and selective triple reuptake inhibitor.

Glaxosmithkline

2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.

Universit£

Synthesis of 3-carbamoylecgonine methyl ester analogues as inhibitors of cocaine binding and dopamine uptake.

University of Maryland

Synthesis of 3-arylecgonine analogues as inhibitors of cocaine binding and dopamine uptake.

University of Maryland

Pyrroloisoquinoline antidepressants. 3. A focus on serotonin.

Mcneil Pharmaceutical

Binding of beta-carbolines at 5-HT(2) serotonin receptors.

Virginia Commonwealth University

Synthesis and in vivo evaluation of a novel 5-HT1A receptor agonist radioligand [O-methyl- 11C]2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)dione in nonhuman primates.

Columbia University

Desvenlafaxine succinate: A new serotonin and norepinephrine reuptake inhibitor.

Wyeth Research

Pharmacological and genetic characterization of two selective serotonin transporter ligands: 2-[2-(dimethylaminomethylphenylthio)]-5-fluoromethylphenylamine (AFM) and 3-amino-4-[2-(dimethylaminomethyl-phenylthio)]benzonitrile (DASB).

National Institutes of Health

Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist.

Case Western Reserve University

In vitro receptor screening of pure constituents of St. John's wort reveals novel interactions with a number of GPCRs.

WestfÄLische Wilhelms-UniversitÄ

The in vitro pharmacology of the beta-adrenergic receptor pet ligand (s)-fluorocarazolol reveals high affinity for cloned beta-adrenergic receptors and moderate affinity for the human 5-HT1A receptor.

Case Western Reserve University