null
SMILES COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(C)=O
InChI Key InChIKey=HUFOZJXAKZVRNJ-UHFFFAOYSA-N
PDB links: 2 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 149404
Affinity DataIC50: 145nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514) 1. 2.5 uL-4x Test Compound or 100 nL 100x plus 2.4...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
BETTA PHARMACEUTICALS CO., LTD.
US Patent
BETTA PHARMACEUTICALS CO., LTD.
US Patent
Affinity DataIC50: 108nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
BETTA PHARMACEUTICALS CO., LTD.
US Patent
BETTA PHARMACEUTICALS CO., LTD.
US Patent
Affinity DataIC50: 16.6nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
BETTA PHARMACEUTICALS CO., LTD.
US Patent
BETTA PHARMACEUTICALS CO., LTD.
US Patent
Affinity DataIC50: 13.7nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
BETTA PHARMACEUTICALS CO., LTD.
US Patent
BETTA PHARMACEUTICALS CO., LTD.
US Patent
Affinity DataIC50: 101nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair