null
SMILES C[C@H]1CC[C@H](Cn2c(nc3nc(nc(-c4cncc(Cl)c4)c23)-c2noc(=O)[nH]2)N2CCOC[C@H]2c2ccccc2F)CC1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 224173
TargetE3 ubiquitin-protein ligase Mdm2 [17-125](Homo sapiens (Human))
Merck Sharp & Dohme Corp.
US Patent
Merck Sharp & Dohme Corp.
US Patent
Affinity DataIC50: 0.585nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair