null
SMILES Cc1ccc(cn1)-c1c(nc(N2CCC(N)CC2)n(C)c1=O)-c1ccc(C#N)c(F)c1
InChI Key InChIKey=PVAIJGPZPUEVFH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 283218
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.
US Patent
CELGENE QUANTICEL RESEARCH, INC.
US Patent
Affinity DataIC50: 100nMAssay Description:To analyze LSD1 inhibitor efficacy in cells, a CD11b flow cytometry assay was performed. LSD1 inhibition induces CD11b expression in THP-1 (AML) cell...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.
US Patent
CELGENE QUANTICEL RESEARCH, INC.
US Patent
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair