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SMILES Oc1ccc(\C=C2\S\C(NC2=O)=N\c2nccs2)cc1

InChI Key InChIKey=OLCHTIJXNVKOCF-JXMROGBWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24513   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Aristotle University

LigandPNGBDBM24513((2E,5E)-5-[(4-hydroxyphenyl)methylidene]-2-(1,3-th...)copy SMILEScopy InChI
Affinity DataKi:  3.88E+5nM ΔG°:  -4.65kcal/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251GGDPubMed