null

SMILES Cc1c(OC(F)F)c(ccc1S(=O)(=O)NC(C)(C)C)-c1sc(nc1CC1CCCCC1)C(=O)N[C@H]1C[C@@H](C1)C(O)=O

InChI Key InChIKey=NSAOHDFDPAPARQ-IYARVYRRSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 392080   

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM392080(US10301272, Example 7/13)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding to RORγ was performed as follows: DNA encodin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S184TJUS Patent
TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM392080(US10301272, Example 7/13)copy SMILEScopy InChI
Affinity DataIC50: 3.98nMAssay Description:Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S184TJUS Patent
TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM392080(US10301272, Example 7/13)copy SMILEScopy InChI
Affinity DataIC50: 3.98nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S184TJUS Patent