null

SMILES NC1=N[C@]2(CN(C[C@H]2CS1)c1ncc(F)cn1)c1cc(NC(=O)c2ncc(F)cc2F)ccc1F

InChI Key InChIKey=LNRQLHAIEKKCPQ-SAHAZLINSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 150693   

TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institutes for Biological Sciences

LigandPNGBDBM150693(US8987254, 8 | US9999624, 9)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20× in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1MZBUS Patent