null

SMILES NC(=O)c1cccc(CN2[C@H](CCc3ccc(F)cc3)[C@@H](O)[C@@H](Cc3ccc(F)cc3)N(Cc3cccc(c3)C(N)=O)C2=O)c1

InChI Key InChIKey=HHKWKXOCHWLVQU-XWHIBYANSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 1101   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1101((4R,5R,6R)-Tetrahydro-1,3-bis[(3-carboxamidophenyl...)copy SMILEScopy InChI
Affinity DataKi:  0.310nM ΔG°:  -13.5kcal/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1101((4R,5R,6R)-Tetrahydro-1,3-bis[(3-carboxamidophenyl...)copy SMILEScopy InChI
Affinity DataKi:  0.310nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed