null

SMILES CC1(C)N=C(N(C[C@@H]2CCN(C2)C(=O)C2CC2)C1=O)c1ccc(cc1)-c1ccc2[nH]ccc2c1

InChI Key InChIKey=YUWNTCLBUZQGFQ-GOSISDBHSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50119580   

Target1,5-anhydro-D-fructose reductase(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50119580(CHEMBL3617741 | US10413545, Compound 1 | US9718813...)copy SMILEScopy InChI
Affinity DataIC50: 138nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3PJBUS Patent
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50119580(CHEMBL3617741 | US10413545, Compound 1 | US9718813...)copy SMILEScopy InChI
Affinity DataIC50: 47.9nMpH: 7.5 T: 2°CAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3PJBUS Patent