null
SMILES OC1c2c(CC1(F)F)c(Oc1cc(F)cc(c1)C#N)ccc2S(=O)(=O)C(F)F
InChI Key InChIKey=MXUSGDMIHGLCNC-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 372972
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Peloton Therapeutics, Inc.
Curated by ChEMBL
Peloton Therapeutics, Inc.
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Antagonist activity at HIF-2alpha in human 786-O cells co-expressing HIF responsive element after 24 hrs by ONE-Glo luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Peloton Therapeutics, Inc.
Curated by ChEMBL
Peloton Therapeutics, Inc.
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Binding affinity to His-tagged HIF-2alpha PAS-B domain (unknown origin) after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair