null

SMILES O[C@H]1c2c(CC1(F)F)c(Oc1cc(F)cc(c1)C#N)ccc2S(=O)(=O)C(F)(F)F

InChI Key InChIKey=QAODNBXSDBLNTQ-HNNXBMFYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 373015   

TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Peloton Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM373015(US10597366, Compound 185 | US9896418, Compound 185)copy SMILEScopy InChI
Affinity DataEC50: <5nMAssay Description:Antagonist activity at HIF-2alpha in human 786-O cells co-expressing HIF responsive element after 24 hrs by ONE-Glo luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H997RJPubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Peloton Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM373015(US10597366, Compound 185 | US9896418, Compound 185)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Binding affinity to His-tagged HIF-2alpha PAS-B domain (unknown origin) after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H997RJPubMed