null

SMILES OC(=O)P(O)(O)=O

InChI Key InChIKey=ZJAOAACCNHFJAH-UHFFFAOYSA-N

PDB links: 8 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50011181   

TargetReverse transcriptase(Human immunodeficiency virus 1)
McGill University

Curated by ChEMBL
LigandPNGBDBM50011181((PFA)dihydroxyphosphinecarboxylic acid oxide | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase E89T mutant assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9R32PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
McGill University

Curated by ChEMBL
LigandPNGBDBM50011181((PFA)dihydroxyphosphinecarboxylic acid oxide | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase M184V mutant assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9R32PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
McGill University

Curated by ChEMBL
LigandPNGBDBM50011181((PFA)dihydroxyphosphinecarboxylic acid oxide | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 polymerase using PPT57 DNA/Cy5-labeled PPT24 as template/primer preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q270842CPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
McGill University

Curated by ChEMBL
LigandPNGBDBM50011181((PFA)dihydroxyphosphinecarboxylic acid oxide | CHE...)copy SMILEScopy InChI
Affinity DataKd:  400nMAssay Description:Binding affinity to HIV1 reverse transcriptase p66/p51-polypurine tract primer complex in presence of Mg2+ ions by band shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43WW0PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
McGill University

Curated by ChEMBL
LigandPNGBDBM50011181((PFA)dihydroxyphosphinecarboxylic acid oxide | CHE...)copy SMILEScopy InChI
Affinity DataKd:  1.39E+4nMAssay Description:Binding affinity to HIV1 reverse transcriptase p66/p51-polypurine tract primer complex in absence of Mg2+ ions by band shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43WW0PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
McGill University

Curated by ChEMBL
LigandPNGBDBM50011181((PFA)dihydroxyphosphinecarboxylic acid oxide | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase K65R mutant assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9R32PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
McGill University

Curated by ChEMBL
LigandPNGBDBM50011181((PFA)dihydroxyphosphinecarboxylic acid oxide | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9R32PubMed