null
SMILES Clc1cccc(N2CCN(CCCNC(=O)c3ccc4ccccc4c3)CC2)c1Cl
InChI Key InChIKey=KLMXOIOZHMEERQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50462918
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DAT expressed in HEK293 cells assessed as reduction in [3H]-DA uptake by micro beta scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3H]5-HT uptake by micro beta scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cells after 15 to 20 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cells after 15 to 20 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of [3H]serotonin uptake at human SERT expressed in HEK293 cells after 15 to 20 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of human NET expressed in HEK293 cells assessed as reduction in [3H]-NE uptake by micro beta scintillation counting analysisMore data for this Ligand-Target Pair