null
SMILES CC(C)(C)NC(=O)[C@@H]1CN(Cc2cccnc2)CCN1C[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12
InChI Key InChIKey=CBVCZFGXHXORBI-PXQQMZJSSA-N
PDB links: 15 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50067593
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Inhibition of wild-type HIV1 BH10 protease expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHIV-1 protease(Human immunodeficiency virus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Inhibition of HIV1 recombinant protease D30N/N88D mutant expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHIV-1 protease(Human immunodeficiency virus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of HIV1 recombinant protease A71V/V82T/I84V mutant expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHIV-1 protease(Human immunodeficiency virus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Inhibition of HIV1 recombinant protease M46I/A71V/V82T/I84V mutant expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHIV-1 protease(Human immunodeficiency virus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Inhibition of HIV1 recombinant protease L10F/L19I/K20R/L33F/E35D/M36I/R41K/F53L/I54V/L63P/H69K/A71V/T74P/I84V/L89M/L90M/I93L mutant expressed in Esch...More data for this Ligand-Target Pair
TargetHIV-1 protease(Human immunodeficiency virus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Inhibition of HIV1 recombinant protease V32I/I47A mutant expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair