BindingDB

null

SMILES CC[N+](CC)(CC)CC

InChI Key InChIKey=CBXCPBUEXACCNR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50149890

Solute carrier family 22 member 1(Homo sapiens (Human))
University of California San Francisco

Curated by ChEMBL

BDBM50149890(CHEMBL9324 | tetraethylammonium)copy SMILEScopy InChI

Ki: 1.63E+5nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair

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Details Article
BindingDB Entry DOI: 10.7270/Q2154KWVPubMed

Targets 7 ▿
- Solute carrier family 22 member 1 8
- Solute carrier family 22 member 2 3
- Solute carrier family 22 member 3 2
- Solute carrier family 22 member 4 1
- High affinity choline transporter 1 1
- Potassium voltage-gated channel subfamily A member 1 1
- Alpha-bungarotoxin 1
Publications 13 ▿
- J Pharmacol Exp Ther 292: 1146-52 (2000) 3
- J Pharmacol Exp Ther 287: 800-5 (1998) 2
- Biochem Biophys Res Commun 296: 644-50 (2002) 2
- Biochem Pharmacol 60: 215-9 (2000) 1
- Am J Physiol Renal Physiol 279: 449-58 (2000) 1
- J Med Chem 60: 2245-2256 (2017) 1
- J Neurochem 67: 145-54 (1996) 1
- Mol Pharmacol 51: 913-21 (1997) 1
- Bioorg Med Chem Lett 20: 4870-7 (2010) 1
- J Pharmacol Exp Ther 286: 354-61 (1998) 1
- Pharm Res 19: 1244-7 (2002) 1
- Biochim Biophys Acta 1466: 315-27 (2000) 1
- Naunyn Schmiedebergs Arch Pharmacol 363: 40-9 (2001) 1
Institutions 10 ▿
- [University of California] 5
- [Kyoto University Hospital, Medical College of Georgia, Kyushu University] 2
- [Kyoto University Hospital, Medical College of Georgia, Kyushu University] 2
- [Kyoto University Hospital, Medical College of Georgia, Kyushu University] 2
- [Universidade do Porto, Dublin Institute of Technology, University of California San Francisco, McGill University, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, The University of Texas M. D. Anderson Cancer Center] 1
- [Universidade do Porto, Dublin Institute of Technology, University of California San Francisco, McGill University, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, The University of Texas M. D. Anderson Cancer Center] 1
- [Universidade do Porto, Dublin Institute of Technology, University of California San Francisco, McGill University, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, The University of Texas M. D. Anderson Cancer Center] 1
- [Universidade do Porto, Dublin Institute of Technology, University of California San Francisco, McGill University, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, The University of Texas M. D. Anderson Cancer Center] 1
- [Universidade do Porto, Dublin Institute of Technology, University of California San Francisco, McGill University, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, The University of Texas M. D. Anderson Cancer Center] 1
- [Universidade do Porto, Dublin Institute of Technology, University of California San Francisco, McGill University, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, The University of Texas M. D. Anderson Cancer Center] 1
Affinity: 5.4E+2 to 1.0E+7 nM▿
- Ki 11
- IC50 6
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 1